Fine-scale mapping in case-control samples using locus scoring and haplotype-sharing methods
نویسندگان
چکیده
منابع مشابه
Fine-scale linkage disequilibrium mapping: a comparison of coalescent-based and haplotype-clustering-based methods
Among the various linkage-disequilibrium (LD) fine-mapping methods, two broad classes have received considerable development recently: those based on coalescent theory and those based on haplotype clustering. Using Genetic Analysis Workshop 15 Problem 3 simulated data, the ability of these two classes to localize the causal variation were compared. Our results suggest that a haplotype-clusterin...
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ژورنال
عنوان ژورنال: BMC Genetics
سال: 2005
ISSN: 1471-2156
DOI: 10.1186/1471-2156-6-s1-s74